WalletHub's 2026 ranking of the best large U.S. cities to start a business places all five top spots in Florida, led by Tampa, Orlando, and Jacksonville — a finding confirmed by multiple news outlets. The ranking is based on 19 metrics including business survival rates, labor costs, and office affordability across 100 cities. DeSantis is using a legitimate research finding as political credit for Florida's business environment, though the post omits that other states also have strong startup cities in the broader top 10 and that business conditions depend on factors beyond state governance (venture capital availability, existing tech clusters, demographic trends).