Labor Secretary Lori Chavez-DeRemer resigned Monday after a Labor Department investigation into misconduct allegations involving her and top staffers, including reported affairs and drinking on the job. She becomes the third Trump Cabinet member to resign or be fired in his second term, following Attorney General Pam Bondi and former DHS Secretary Kristi Noem. The misconduct investigation was nearing completion when her resignation was announced, suggesting the allegations were substantive enough to trigger her departure before findings were fully public.