Trump and Pope Leo XIV are locked in a public feud over the pope's comments on the Iran conflict, with Trump attacking the pontiff and senior administration officials like VP Vance escalating criticism of the Vatican. The dispute marks an unusual clash between a U.S. president and the Catholic Church leadership over foreign policy and religious messaging. Pope Leo has responded by emphasizing the possibility of coexistence despite their differences, while religious experts say Trump's direct attacks on a sitting pope are historically unprecedented.