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Science MagazineonBluesky2d ago
A phase I clinical trial involving children with autism spectrum disorder suggests that deep brain stimulation of the nucleus accumbens may reduce self-harming behavior.
Learn more in #ScienceAdvances: https://scim.ag/4chnXgm
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Context80%
Analysis Summary
Researchers conducted a phase I trial testing deep brain stimulation in the nucleus accumbens (a brain region linked to reward and motivation) to treat self-harming behavior in autistic children, and found promising results. This is preliminary work โ phase I trials are designed to test safety and identify dosing in small groups, not prove effectiveness. The study appears to be real and peer-reviewed, though some experts quoted in coverage express concerns about study design and generalizability to larger populations.
Claims Analysis (1)
โA phase I clinical trial involving children with autism spectrum disorder suggests that deep brain stimulation of the nucleus accumbens may reduce self-harming behavior.โ
Corroborated by Oxford Today coverage of the Science Advances study describing DBS targeting nucleus accumbens for self-injurious behavior in autistic children.
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