A norovirus outbreak aboard the Caribbean Princess cruise ship sickened 115 people (102 passengers and 13 crew members) during a voyage that departed Fort Lauderdale on April 28, 2026, according to CDC reports. Norovirus spreads rapidly in confined environments like cruise ships and typically causes acute gastroenteritis lasting 24-48 hours; the outbreak prompted standard public health response protocols. This is the second major norovirus outbreak on a Princess cruise ship in two months, with the Star Princess reporting over 150 sick in March, suggesting possible systemic issues with sanitation or outbreak prevention procedures across the cruise line's fleet.